Specialized Needle Biopsies
Breast Biopsy Techniques
Many women go through the anxiety provoking experience of being called back
to their breast center when an area of concern is found on their screening
mammogram. If this area persists on the mammogram and/or ultrasound,
the radiologist may recommend a biopsy. The biopsy will provide the pathologist
with material so that a definitive diagnosis can be made. Please remember
that 70 – 90%
of all biopsies will be negative/benign, or not cancer.
Traditionally, when an abnormality presented itself, an excisional, or open
surgical biopsy was performed. In this modern era, most breast biopsies are
done under local anesthetic with some form of needle, in the doctor’s
office, or breast center. There are, however, certain occasions when surgical
biopsy will still be indicated and performed. Needle biopsy offers less disfigurement,
immediate recovery, no general anesthetic with its side effects, and lower
cost. Following is a fairly comprehensive list of the different types of needle
biopsies.
FNA/ FINE NEEDLE ASPIRATION:
This procedure is usually guided by ultrasound, or by palpation/feel of a
mass. A very narrow needle is placed into the lesion, through the anesthetized
skin. Some cells are retrieved and then sent to the pathologist to be evaluated.
CORE NEEDLE BIOPSY:
A small nick is made in the skin after the anesthetic has been administered.
A larger needle is inserted into the suspicious area one or more times. This
is usually a spring- loaded device for quick advancement and sampling. The
benefit over FNA is that more cells and their background tissue are obtained,
giving the pathologist more information from which a diagnosis can be made.
Core needle biopsy can be guided by ultrasound, by palpation/ feel, or by
stereotactic guidance.
STEREOTACTIC NEEDLE BIOPSY:
There are two scenarios currently available. One is an upright unit where
the patient sits up in a chair, and her breast is compressed in a traditional
mammogram unit. The second type is a prone table. In this model, the patient
lies on her tummy, and the affected breast extends through a hole in the table,
and is compressed below by a “mini-mammogram unit.” This second
style reduces the incidence of patient motion, helps to prevent the occasional
light-headed person from fainting, and takes advantage of the natural force
of gravity to help sample tissues deep within the breast, closer to the chest
wall.
Digital stereo x-rays are used to guide the needle or probe to the exact
location of the lesion. A dedicated computer is used to increase the speed,
precision, and ease of the procedure. Multiple samples are then obtained.
The devices most commonly used with stereo biopsies are core needles, and
vacuum assisted probes.
VACUUM ASSISTED PROBE BIOPSIES:
These can be the same size as the more traditional spring-loaded core needles,
or slightly larger. Preparation is the same as for a core needle biopsy. It
differs from the core needle in that the probe does not need to be removed
and replaced into the breast with each sampling. It is inserted once, and
remains in the breast throughout the procedure. It rotates and collects samples
as it goes, using a vacuum to pull the suspicious tissue into it. This device
can collect more tissue in less time than core needles. Another advantage
is that it can deploy a tiny surgical clip into the biopsy cavity, thus allowing
a surgeon to locate the area at a future time, if needed for treatment.
RADIO FREQUENCY INTRODUCERS IN CONJUNCTION WITH HAND HELD BREAST BIOPSY SYSTEMS:
This is the implementation of an electro surgical device that uses radio
frequency to cut tissue in order to reach a lesion. All of these core and
probe devices must traverse breast tissue from the skin to the actual suspicious
area. Sometimes this breast tissue can be very tough, and require much force
to get to the desired area, and occasionally the lesion itself is tough or
rubbery and can deflect the biopsy needle. The radio frequency device can
facilitate a biopsy by making it easier to get from the skin into the lesion.
CRYO-ASSISTED ROTATIONAL CUTTING DEVICES/PROBES:
Another name for this device is “Stick-Freeze” technology. This
is a modification of a core needle biopsy. Again, a small nick is made in
the anesthetized skin. A rather small securing needle is placed within the
suspicious lesion. The surrounding tissue is frozen directly to this needle;
it “sticks” to the needle. A cutting canula, (outer round sheath),
rotates and automatically advances over the securing needle, cutting and obtaining
the tissue that is on the securing needle. This process is fully automated,
hand held, and obtains large tissue samples with fewer passes, or insertions
than many spring loaded core biopsies. Ultrasound is used to guide this type
of biopsy.
The availability of all of these modern, less invasive options have facilitated
the diagnosis of breast disease, making it easier, faster, and less painful.
Now, for the most part, surgery can be reserved for cancer, or precancerous
lesions.
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